Differential phenotypic and genotypic characteristics of qnrS1-harboring plasmids carried by hospital and community commensal enterobacteria

The qnrS1 gene induces reduced susceptibility to fluoroquinolones in enterobacteria. We investigated the structure, antimicrobial susceptibility phenotype, and antimicrobial resistance gene characteristics of qnrS1 plasmids from hospitalized patients and community controls in southern Vietnam. We found that the antimicrobial susceptibilities, resistance gene characteristics, and plasmid structures of qnrS1 plasmids from the hospital differed from those from the community. Our data imply that the characteristics of the two plasmid groups are indicative of distinct selective pressures in the differing environments.

Observed climate variations and change in Vietnam

In this study, observed changes of temperature, rainfall, and some extreme climate indices in Vietnam were investigated by using daily observations during the period 1961-2012. The observed data were collected from 80 meteorological stations for temperature, and from 170 stations for rainfall over the seven climatological sub-regions of Vietnam. Results show that there were insignificant differences between the trends of changes obtained from the 1961-2011 and 1979-2012 periods. Near-surface temperature, including mean (T2m), maximum (Tx) and minimum temperature (Tm), increased consistently at almost all stations. Tm increased faster than Tx. Temperature also increased faster in winter than in summer. Consequently, the number of hot days and warm nights increased whereas the number of cold days, cold nights and cool days decreased. In the northern regions, temperature tended to slightly decrease in May but significantly increased in June. Annual rainfall decreased in the northern area of Vietnam, while it increased at almost all stations in the central regions, and had insignificant trends in the southern sub-region. Changes in some extreme rainfall indices were likely consistent with changes in annual rainfall. Monthly rainfall in the central regions significantly increased from August to December. Rainfall generally increased in May and decreased in June over almost all country.